MIMA is a software for mapping mass-spectrometric (MS) data to corresponding ion-mobility spectrometer (IMS) derived chromatograms. Its focus is the automation of the MS to IMS peak assignment.
Ion-mobility spectrometry is an analytical detection method for volatile substances and is often coupled with mass spectrometry. Peak assignment of MS and IMS data is a frequent operation for identification of indistinct peaks in complex IMS samples. A drawback of a manual comparison of MS and IMS measurements is the high expenditure of time and the requirement of at least two parallel running software tools to compare both chromatograms. MIMA automates this process by generating an IMS Layer from corresponding MS data in comparison with an IMS database. The layer contains the analytes and the corresponding coordinates within the IMS-chromatogram and can be superposed on IMS chromatograms in the IMS analysis software VisualNow.
MIMA is developed at Max Planck Institute Informatik, in cooperation with the KIST Europe, Saarbrücken.
The MIMA software supports three languages: English, German and French.
F. Maurer, Saarland University Medical Center and Saarland University Faculty of Medicine, Homburg, Germany
A.C. Hauschild, Max Planck Institute for Informatics, Saarbrücken, Germany
K. Eisinger, KIST Europe, Saarbrücken, Germany
Maurer F, Hauschild AC, Eisinger K, Baumbach J, Mayor A, Baumbach JI (2014). MIMA – A software for analyte identification in MCC/IMS chromatograms by mapping accompanying GC/MS measurements. Int. J. Ion Mobil. Spec. Volume 17, Issue 2, pp 95-101. Springer Link